Estrogen metabolism is an important concept for both men and women. When discussing hormones, we need to consider both production and metabolism. Estrogen is just one hormone in which metabolism is key.
1. Reduce Toxic Exposure
Personal Care Products
Key ingredients to AVOID (Often found in: Air fresheners, deodorants, Fabric softeners, Scented candles, Body perfumes) 
- chemical colourings, chemical preservatives
- TALC, organochlorides
- Diethanolamine (DEA), Monoe Thanolamine (MEA), triethanolamine (TEA)
- Paraben Preservatives: methyl, propyl, butyl, isobutyl, and ethyl
- Mineral oil: petrolatum, petroleum jelly (liquid paraffinum, paraffin oil, paraffin wax, posh mineral oil
- Propylene glycol/butylene glycol
- Silicone derived emollients: dimethicone, dimethicone copolyol, cyclomethicone
- Dibutyl phthalate
- BHT (butilated hydroxytoluene)/ BHA (butilated hydroxyanisole)
- benzalkonium chloride and benzethonium chloride
- triclosan and triclocarban parfume
Look for: organic, plant sources, toxin-free, safe packaging, and safe processing methods
Food and Nutrition
Consider following the Environmental Working Group’s Clean 15 and Dirty Dozen. These are lists which make recommendations regarding which foods to eat organic (dirty dozen) and which can be eaten of the conventionally grown variety (clean 15). For more information please check out the Environmental Working Group’s website, by clicking here.
Consider removing Dairy. There is research showing that conventionally raised dairy contains significant amounts of estrogen metabolites, especially the bad types . Click here to see that article.
2. Dietary Changes
Certain nutrients in specific foods are known to have favourable effects on estrogen metabolism:
- ECGC (green tea) 
- Ellagic acid (berries) 
Eat lots of dark Leafy greens 
Increase Dietary fiber (30 grams/day) 
Drink adequate Water (1-2 liters/ day) 
Incorporate olive oil into your diet 
Eat lots of foods that help liver detox: such as cruciferous veggies, garlic, beets, spices etc
Eat lots of foods and nutrients that support healthy bile flow: such as artichoke leaf , Vitamin C, B6, Folic acid, B12, choline, inositol, taurine, methionine, betaine
Limit Caffeine and alcohol 
3. Support Routes of Elimination (Sweating, Bowel, Kidneys)
Sweating and Hydrotherapy: allows toxins to leave through the skin. Try dry brushing. Avoid shower and bath products which may block the pores. When sweating, replace lost fluid to protect against dehydration.
Exercise: helps circulation and muscle contraction, both of which help estrogen metabolism and detoxification.
Digestive Health: promote good gut bacteria diversity. When we eat veggies, the gut bacteria make good phytochemicals called enterolignans. These play important roles in prevention of cancer and chronic disease as well as estrogen metabolism . The more diverse our gut bacteria, the more enterolignans we will have. We have even seen positive association in prevention of bone loss; a specific probiotic strain called L. reuteri has been helpful in rat models .
See a Naturopath for personalized suggestions regarding:
- Botanicals, micronutrients, medical foods, prebiotics, probiotics
- Specialized lab testing
5. Support Methylation if necessary
*This is something that could be identified on specialized testing; this is an important step in estrogen metabolism.
Methylation relies on proper COMT enzymes, and it is known to be a fairly complex process. We can support COMT with:
- Methionine especially important if low homocysteine
- B2, B6 B12
- Folic acid (also as folinic acid, 5-formyl THF, 5-MTHF
- TMG (betaine)
Glutathione is the master detoxifier of phase II detox. It too must be supported. If reduced glutathione, the following are useful:
- Reduced glutathione (1-3 g/day)
- N-acetyl-cysteine (2000 mg/day)
- Lipoic acid (1,000 mg/day)
- Whey protein concentrates 2-3 servings/day
- Magnesium (400 mg)
- Vitamin C (500+mg)
- Vitamin E (mixed tocopherols) (400 IU)
- Pantothenic acid (500 mg/day)
- SAMe 400-800 mg/day
- Glycine and Glutamine
- B vitamins (B2, B6, B12, 5MTHF)
- Turmeric extract, grape seed extract
- Bilberry, strawberry/black raspberry extracts
- Antioxidants (to discourage formation of quinone compounds)
- Glutathione is useful for monitoring melatonin’s protective role in cell damage
6. Reduce Stress
Physical Exercise, meditation, deep breathing, yoga etc.
COMT Mutations are associated with nervousness, anxiety, increased sensitivity to pain; so addressing COMT can be quite beneficial.
- Bowel support: fiber
- Kidney support: hydration, antioxidants
- Liver support: phase 1 and 2 support
- Stress reduction
About the Author
I'm Johann de Chickera, a Naturopathic Doctor, practicing in Ontario, Canada. My clinical practice relies on keeping up with the most up-to-date research and continued education. This blog serves as a way to provide others with a compilation of everything I've learned along the way.
If you'd like to see me in practice, please click the Appointments tab at the top of this page.